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Early initiation of folic acid supplementation (210 mg/kg/day) is recommended, and patients who begin supplementation before the age of 6 years tend to have a better prognosis than those who start supplementation after the age of 6 years [101]

Modern formulations often include: Reduced glutathione for better bioavailability Supporting antioxidants such as vitamin C Plant compounds that protect cellular health While results may take longer than IV therapy, tablets are generally more practical for long-term wellness routines