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In an animal study using 5-dihydrotestosterone + insulin treatment to simulate a miscarriage model in PCOS patients, NAC supplementation improved fetal survival rates in model mice by protecting mitochondrial function, restoring the balance of SOD1 and the Keap1/Nrf2 antioxidant response, reducing excessive ROS production, and mitigating placental formation defects [57]

Link to Study Resources: Chang, C

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10 Pdcd4 has been demonstrated to inhibit tumor promotion and progression, 13 whose expression is often downregulated in colorectal cancer