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In summary, an intact prolactin diurnal rhythm may play a crucial role in maintaining metabolic homeostasis, whereas its disruption is associated with impaired glucose homeostasis, adipose tissue dysfunction, and an increased risk of metabolic comorbidities

Gut bacteria can convert the intake of choline into TMA, further generating TMAO in the liver, which reduces the bioavailability of choline and increases the lipid content of the newborn liver, leading to NAFLD and even nonalcoholic steatohepatitis

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