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For example, hepatocytes contain high levels of alpha GST and serum alpha GST has been found to be an indicator of hepatocyte injury in transplantation, toxicity and viral infections

Sharma A, Kumar A, Torre BGdela, Albericio F

The existence of monospecific nave CD8+ T cells in healthy patients suggests a trigger that induces their differentiation into memory and effector T cells in AAb+ and T1D patients ( in vitro models from AAb+ or T1D patients, such as hPSC-derived cells, will help address these questions