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Along with the presence of high- and low-abundant microbes, the maintenance of the intestinal epithelial barrier is further maintained by critical players, including immune cells (mononuclear macrophages, T-cells, and innate lymphoid cells), enteric glial cells (EGCs), and the intrinsic/extrinsic enteric-associated-neurons (iEANs/eEANs) of the ENS (Muller et al., 2020b)
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Nonmotor versus motor symptoms: how much do they matter to health status in Parkinsons disease
The administration of an ultra-low dose of THC (0.0002 mg/kg body weight) induced a marked increase in insulin-like growth factor 2 (IGF2), a peptide known to decline with age and to exert neuroprotective effects, particularly in hippocampus-dependent memory and cognitive processes
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