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Description

& Yiu, W

15 Of the antimicrobials, antitubercular drugs (especially isoniazid) are believed to be the most common causes, followed by trimethoprim-sulfamethoxazole

In our model, NAPQI is produced in the liver by three cytochrome oxidases, CYP2E1, CYP3A4, and CYP1A2

The cells were harvested and disrupted at 4C with 425600-m (diameter) glass beads in buffer G [10 mM Tris-HCl (pH 7.5), 300 mM sorbitol, 100 mM NaCl, 5 mM MgCl 2 , 1 mM EDTA, and 1 M pepstatin A]