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FOXO4 is a forkhead box O transcription factor that mediates various signaling pathways to maintain cellular homeostasis 33

Research applications Research applications Investigation of FOXO4p53 interaction disruption and downstream apoptotic signaling In vitro studies of cellular senescence, senolysis, and age-related cell clearance Combination studies with chemotherapeutics, targeted agents, or senolytic compounds Mechanistic assays of apoptosis markers, mitochondrial dysfunction, and cell viability For laboratory research use only

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2018. MOTS-c translocates to the nucleus during metabolic stress