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Analytical Workflow Five stages from sample receipt to MoA-annotated deliverable: 1 Sample preparation and quality assessment Drug-treated and control samples (cells, tissue, plasma, or culture supernatant) are processed by established quenching and extraction protocols matched to the sample matrix methanol/water for polar metabolites, MTBE-methanol-water for lipidomic coverage, or a combined biphasic extraction for broadest coverage

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This is important information because once we identify the various factors that relate to our risk, it may offer up opportunities to change our cognitive destiny