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Ultimately, our proposed paracrine mechanism would enable rapid, dynamic coordination of intra-islet DA signaling to further fine-tune regulation of insulin and glucagon secretion

Based on their results, the authors proposed that PBM can modulate the neuronal connectivity during the transition from acute to subacute phases in TBI (23-week time-point) in the frontal-parietal regions

Apelin exhibits strong metabolic and cardiovascular biology, with failure driven largely by exposure-related hemodynamic effects and lack of signaling bias, suggesting failed pharmacology rather than failed biology

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