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In response to stress, low expression of PGC-1 results in a reduction in ATP synthesis and an increase in ROS production, which in turn leads to dopamine neuron loss or damage

The integration of IV nutrient therapy with conventional cancer treatment requires careful coordination and communication among all members of the healthcare team

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To systematically summarize the current potential therapeutic strategies targeting amino acid metabolism to regulate macrophage polarization, Table 1 outlines representative agents, their targets, their effects on macrophage polarization, and their stages of development