allodynia from glp 1

allodynia from glp 1 GLP-1 Drugs: New Reports of Dysesthesia and PDF) Allodynia and Dysesthesia Associated

Name: allodynia from glp 1 GLP-1 Drugs: New Reports of Dysesthesia and PDF) Allodynia and Dysesthesia Associated
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Description

One of the most common reasons patients discontinue GLP-1 RA treatment is due to gastrointestinal side effects, which could be attributed to the markedly high GLP-1 RA levels

Regulatory agencies in some regions have issued warnings that these extreme, non-therapeutic doses can put undue stress on the kidneys and liver

Subsequent activation of signaling pathways-including TGF-, Wnt, renin-angiotensin-aldosterone system (RAAS), and Notch-elicits myofibroblast differentiation and accelerate ECM overproduction (Qian et al., 2022)

J Pharm Biomed Anal 10:645650