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This effect is stronger after the complete normalisation of body weight/glucose metabolism

Genetic Predispositions and Biomarker Context for Semaglutide Selection Emerging research suggests genetic variants in GLP-1 receptor (GLP1R), GIPR (glucose-dependent insulinotropic peptide receptor), and obesity-related genes (FTO, MC4R) may correlate with individual GLP-1 efficacy and side effect tolerance

Yildirim, A., Gumus, M., Dalga, S., Sahin, Y

While GLP-1 medication do not directly increase energy in the traditional sense (like a stimulant would), it helps by regulating blood sugar, reducing body weight, and improving metabolic health, all of which can lead to more consistent and sustainable energy levels