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Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats

Ferroptosis in disease Ferroptosis is involved in various diseases, including neurodegenerative disorders, organ injury-related conditions, and cancer [3-4]

Junctional Complex The junctional complex is compromised by tight junctions (TJs), adherens junctions (AJs), and GAP junctions (GJs) (12, 13)

Researchers designing combination protocols typically run controls with each compound in isolation alongside the combination arms to distinguish additive from synergistic effects and to identify which compound is driving each observed outcome