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However, the requirement for HSL phosphorylation has recently been challenged as studies by the Granneman group elegantly show that direct activation of PNPLA2 in the absence of PKA stimulation is sensitive to HSL inhibition, suggesting that PNPLA2-mediated generation of DAG is sufficient to promote HSL activity (49)

10.1089/ars.2009.2695 Antioxid Redox Signal

Lee, PhD, MRCP, MBChB, and colleagues confirmed that the cardiovascular (CV) and renal benefits of long-acting glucagon-like peptide 1 receptor agonists (GLP-1RAs) for patients with type 2 diabetes (T2D) extend to both subcutaneous and oral formulations

If the levels a re lower recovery with supportive treatment is the rule