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The production of ROS is linked to the overexpression of a misfolded disulphide-bonded protein, carboxypeptidase Y (CPY * )

Liver tissue was crushed and prepared with previously described methods to separate the aqueous, lipid, and protein layers, 9 and sent to the Department of Biochemistry at the University of Cambridge, Cambridge, UK, where liquid chromatography mass spectrometry was undertaken

Low melatonin secretion during the night is observed in FM patients caused by reactive oxygen species