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The more aggressive weight loss may come with a higher side effect burden, particularly during the dose escalation phase

You can develop skin cancer on the inner thigh, outer thigh, knee, knee cap, shin, calf, or even the back of the leg, or any other part of the leg that has been exposed to ultraviolet radiation

If symptoms continue or intensify, its worth revisiting your treatment plan with your provider to explore possible adjustments

Here, Ekihiro Seki & team implicate the fungal sensing adaptor protein CARD9 in maintaining gut barrier integrity under metabolic stress, finding that the loss of fungal sensing exacerbates liver injury in a murine model of MASLD