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These include the gut-derived hormones, such as the potent incretins glucagon-like polypeptide-1 (GLP-1) and gastric inhibitory peptide (GIP) and the -cell hormone amylin

The study, part of a multicenter, randomized, double-blind trial conducted at 42 institutions in the United States, quantitatively analyzed changes in total fat mass using dual-energy X-ray absorptiometry, or DXA, to track shifts in the ratio between fat and muscle

Evaluate real-world clinical use, including disease impact, safety profiles, and contraindications, as well as further uses of these medicines as co- and poly-agonists in applications beyond diabetes and obesity

By doing so, in atherosclerotic plaques from murine aortas, GLP-1RAs regulate proinflammatory mediators and the phenotype of immune cells