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CrossRef Anti-obesity effects of Lactiplantibacillus plantarum SKO-001 in high-fat diet-induced obese mice Mi Jin Choi, Hana Yu, Jea Il Kim, Hee Seo, Ju Gyeong Kim, Seul-Ki Kim, Hak Sung Lee, Hyae Gyeong Cheon European Journal of Nutrition.2023

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The mechanism is direct: GHRP-6 binds to the ghrelin receptor, and ghrelin is the hunger hormone

For trips shorter than this period in moderate climates, you may not need continuous refrigeration, though it remains ideal to refrigerate whenever possible to maximize medication lifespan