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The assay basis was not always clear
However, there are multiple cases of valproic acid-induced hyperammonemia reported in older male patients with both chronic valproic acid use and recent initiation
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Treatment of MAT deficiency includes supplementation with betaine, folic acid, vitamin B6, and vitamin B12, and a methionine-restricted diet.14 Folate, Vitamin B6, and Vitamin B12 Deficiencies Adequate levels of folate, vitamin B6, and vitamin B12 are needed to properly metabolize homocysteine
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