Como buena prctica, conviene trazar un plan simple: definir presupuesto, calendarizar sesiones y medir el rendimiento de las jugadas con mtricas personales, evitando perseguir prdidas y celebrando ganancias con moderacin
Source: Jastreboff et al., NEJM 2023 TRIUMPH-4 Phase 3 (68 weeks, 445 participants) Phase 2 Type 2 Diabetes Trial (36 weeks, 281 participants) In the type 2 diabetes population, weight loss was lower than in the obesity trial which is consistent with the pattern seen across all GLP-1 drugs
Its the moment two separate clocks start running, the anesthesia one and the results one, and disclosing early is the one lever you actually get to pull yourself
The two drugs havent been compared directly in a head-to-head trial, and the populations studied differ, so the gap may narrow once like-for-like data is available