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Introduction Antioxidants are enzymatic (endogenous) or non-enzymatic (exogenous) chemicals that form a major line of defense against reactive oxygen species (ROS) by inhibiting the propagation of free radicals or interrupting their formation, resulting in reduced oxidative stress, improved immune function, and increased healthy longevity

In these cases, topical products will not make a visible difference in the hang of the skin

They stimulate the synthesis of collagen and glycosaminoglycans, which improves skin firmness and elasticity

APE1 was also one of the many non-regulatory proteins involved in cancer survival signaling pathways, and could be used as a therapeutic target in the treatment of multiple types of tumor cells [24]