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During the course of imaging (20 min), mice received isoflurane/O 2 and were maintained at 37 C by the heated bed on the scanner

"And so what we've learned over the years is that hitting the system in more than one place can often bring additive weight loss." While losing a large amount of weight may be the goal for some people, for others, it is not, which is why it's important that multiple drugs are available, according to Aronne

The use of liraglutide successfully lessened the disease score in EAE mice compared to mice without liraglutide and delayed the onset of EAE by nearly three days

During follow-up, 12 patients in the oral semaglutide (10.4%) and 11 patients in the subcutaneous semaglutide (6.2%%) group discontinued treatment due to side effects, without significant differences between the two formulations ( p = 0.27) (Supplementry Figure S2o)