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What the Data Shows The Phase 2 trial of retatrutide, published in the New England Journal of Medicine in 2023, enrolled 338 adults with obesity or overweight with a weight-related condition (5)

GLP-1 receptor agonists work by mimicking incretin hormones that regulate insulin secretion, appetite signalling, and gastric function as described in clinical pharmacology literature [1]

The strong effect it has on average weight loss means retatrutide could be good for people who have not got their weight loss goals from other treatments