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HCMV has developed strategies to evade humoral immunity, as inferred from frequent super-infection with new HCMV strains in healthy individuals (Ross et al, 2010), virus transmission in seropositive pregnant women (Lilleri et al, 2013), and low efficacy of HCMV IgG prophylaxis in solid organ and hematopoietic stem cell transplant recipients (Hodson et al, 2007

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The increasing number of reports about these adverse effects has led to growing scrutiny and legal challenges against the manufacturers, Novo Nordisk and Eli Lilly