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Strategies targeting mutant p53 restore the wild-type conformation and activity of mutant proteins and promote mutant p53 degradation by disrupting the stability of mutant p53

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Hepatic TH signaling governs the GLP-1 production and glucose homeostasis As the glucose-lowering effect has been reported for either TR-selective agonist or liver-specific TR-selective agonist in obese mice 17,18 , we then employed mice lacking TR in the liver (LTRKO mice) we developed recently (Supplementary Fig

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