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432,433,434 However, -cells exposed to diabetes and hyperglycemia exhibit striking changes in metabolism

This connection is particularly relevant for substances that temporarily increase serotonin, such as alcohol and stimulants, and underscores serotonins role in addiction prediction

This is probably due to the fact that GLP-1R is distributed both in the peripheral organs and in the central nervous system, the system that regulates most body functions [29]

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