A retrospective analysis of 461,382 adults treated with GLP-1 receptor agonists found that nutritional deficiencies were diagnosed in 12.7% of patients within six months and 22.4% within twelve months, with vitamin D deficiency the most common at roughly 13.6% by the one-year mark
GLP-1 treatments like Wegovy, Zepbound, Mounjaro, and compounded Semaglutide and Tirzepatide are helping people see real, lasting weight loss results, often without the need for surgery
However, its important to note that both Semaglutide GLP-1 and Liraglutide can cause gastrointestinal side effects, with a slightly higher incidence in patients taking Semaglutide GLP-1
In subsequent Phase 2 trials, once-weekly subcutaneous injections of retatrutide at doses of 4 mg, 8 mg, and 12 mg resulted in marked improvements in glycemic control compared to placebo, along with substantial weight loss when contrasted with placebo and dulaglutide (1.5 mg)