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With that said, the most common side effects of compounded semaglutide include: Dizziness Fatigue Diarrhea Constipation Bloating or gas Headache Nausea Vomiting Stomach cramping or pain If you start to notice these or any other more severe side effects of taking compounded semaglutide, you should stop taking your weekly injections and contact your doctor immediately to seek medical attention and discuss your options