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PlexusDx offers both molecules through its Weight Management Protocols as Tirzepatide Injection, Tirzepatide Oral, Semaglutide Injection, and Semaglutide Oral at published per-protocol pricing

North Carolina officials blamed Medicaid funding shortfalls when taking the same step in November, and Michigan said it intends to ban the use of the drugs except for the morbidly obese on Medicaid

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The FDA's December 22, 2025 approval of the first oral GLP-1 for obesity marks an inflection point in treatment options