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Hormonal fluctuations can affect dopamine and serotonin, which influence motivation and reward

Vitamins B12, B6, and folate are essential for the synthesis of cystathionine synthase and cystathionase (B6) and methionine synthase (B12)

Competition with essential nutrients and replacement of metallic cofactors in enzymes impair fundamental metabolic processes, including photosynthesis, respiration, and nutrient assimilation