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Glutathione attenuated gill autophagy under hypoxia stress Autophagy is a tightly regulated cellular process that degrades and recycles dysfunctional organelles and other cellular materials through the lysosomal pathway [49]

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Compensatory overproduction of pancreatic islets and eventual development of hyperinsulinemia, result in elevated hepatic synthesis and accumulation of total cholesterol (TC) and elevated low-density lipoprotein (LDL) levels, leading to inactivation of the enzyme LDL lipase, which is critical for cholesterol clearance