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GLP-1GIP Coagonists: Improving Glycemic Control and Weight Loss While Reducing Nausea and Emesis Approximately 30 years ago, the discovery was made that a compound in the venom-laced saliva of the Gila monster shared properties similar to those of human GLP-1, but unlike the endogenous active form of GLP-1 [i.e., GLP-1(7-36)], this compound was resistant to enzymatic degradation by dipeptidyl peptidase IV

'The toxins have evolved to do bad stuff, so harnessing an entire venom cocktail for good would be difficult

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