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The therapeutic potential of Mel-HA-MN was further validated in AIA rodent models, where repeated applications of the microneedle patch successfully reduced paw swelling, maintained body weight and preserved cartilage integrity

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The STEP-1 trial tested the effect of high-dose semaglutide to produce weight loss in people with obesity who do not have diabetes

6s) 84,85 , which is an indicator of mitochondrial workload