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Creatine may be appropriate for teen athletes (16+) who participate in serious, competitive, and supervised training, with healthcare provider guidance, under adult supervision

Most users experience a net improvement in body composition over an 8 to 12-week cycle, particularly when combined with exercise and a moderate caloric deficit

In overweight/obese women on a reduced-calorie diet: A study of 77 healthy but sedentary overweight or obese women (ages 2050) on a reduced-calorie diet found that those who took alpha-lipoic acid (300 mg per day as three 100 mg capsules with meals) or a combination of alpha-lipoic acid and the omega-3 fatty acid EPA (1,300 mg per day) for 10 weeks lost significantly more weight an average of 15 lbs and 14 lbs, respectively compared to those who took EPA only or placebo (average weight loss of 12 lbs and 11.5 lbs, respectively)

According to a recent meta-analysis, the percentage of people suffering chronic fatigue 12 weeks or more after exposure to COVID-19 was 0.32, whereas cognitive impairment was 0.22 [66]