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who used forearm strain-gauge plethysmography to assess the effects of metformin on forearm blood flow following the intra-brachial artery administration of acetylcholine versus responses to the endothelium-independent vasodilators, sodium nitroprusside and verapamil, in patients with T2DM (106)

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Energy and Motivation May Fluctuate Some patients report: Increased fatigue Irritability Mental distraction Decreased enthusiasm for routine habits These symptoms often relate to changes in appetite hormones and blood sugar stability

Can GLP-1 medications like Ozempic help with weight loss even without diabetes