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In clinical and preclinical studies, the CJC-1295/Ipamorelin combination has been shown to increase IGF-1 levels, improve body composition, and enhance sleep quality, specifically the slow-wave (deep) sleep stages during which the majority of natural GH secretion occurs [15]

It also showed a good safety profile with minimal side effects

Thus, for anti-aging purposes, restoration of frequent, regularly occurring GH pulses is a very important physiological effect because it represents recrudescence of spontaneous GHRH neuronal activity bursts, enhancing the quality of feedback control dynamics