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These strategies produce substantially different metabolic consequences, tissue distribution patterns, and research applications despite their shared endpoint of increased IGF-1 bioavailability

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coptidis to set the pH of mother liquor to 10, the concentration of hydrochloric acid in the membrane to 0.3 mol/L, the ratio of oil to 5 and the ratio of milk to water to 1:4 to obtain a good separation and enrichment of BBR (Guoping and Song, 2009)