In iGlarLixi (insulin glargine: LIXI = 1:1) study, adult Japanese patients with T2DM lost more weight compared to the iGlar (insulin glargine U100) study (-0.51 kg vs
Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: A systematic review and meta-analysis of cardiovascular outcome trials
Lean options are generally better tolerated when gastric emptying is delayed: Poultry: Skinless chicken or turkey breast (2630g protein per 3.5 oz serving) Fish and seafood: Salmon, cod, shrimp, tuna (2025g per 3.5 oz) Eggs: Whole eggs or egg whites (6g per large egg, 3.6g per white) Low-fat dairy: Greek yogurt (1520g per 6 oz), cottage cheese (14g per cup), skim milk (8g per cup) Lean beef or pork: Sirloin, tenderloin, or pork loin (2226g per 3.5 oz) Plant-based proteins are valuable for patients who prefer vegetarian options or want to diversify protein sources, though they may require larger portions to meet protein goals: Legumes: Lentils, chickpeas, black beans (1518g per cooked cup) Soy products: Tofu (10g per cup), tempeh (15g per cup), edamame (17g per cup) Nuts and seeds: Almonds, peanut butter, chia seeds (68g per cup, though calorie-dense) Whole grains: Quinoa (8g per cooked cup), though primarily a carbohydrate source Protein supplements can be particularly useful when solid food intake is limited: Whey or plant-based protein powders (2030g per scoop) Ready-to-drink protein shakes Protein-fortified foods like high-protein yogurt or milk Patients should be counseled to choose lean preparationsgrilled, baked, or steamed rather than friedand to be mindful of added fats that can exacerbate nausea or early satiety
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These side effects are typically mild to moderate in severity and tend to improve over time
