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Chronic complications of diabetes are categorized into macrovascular and microvascular complications, and diabetic microvascular complications mainly include diabetic kidney disease (DKD), diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and diabetic cardiomyopathy (DCM)

Among the saline spray group, 22.4% said the treatments efficacy was good 6.1% said it was very good, and 46.9% said it was poor

This mechanistic overlap highlights a need for potential therapeutic targeting of ferroptosis

Clinicians should be aware of important safety considerations, including the risk of gallbladder disease (cholelithiasis, cholecystitis) and rare reports of intestinal obstruction or ileus