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Approved ASO drugs target exon 45 (casimersen), 264,496 exon 51 (eteplirsen), 497,498 and exon 53 (golodirsen and viltolarsen) 80,263 to induce specific exon skipping in the dystrophin gene, thus delaying disease progression

The compound's effects on collagen deposition are mediated through complex interactions with transforming growth factor-beta (TGF-) signaling

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ANTECEDENTES DE LA INVENCIN La obesidad se ha tornado en una de las mayores amenazas para la poblacin debido a su creciente incidencia y por su capacidad de inducir patologas crnicas en casi todos los sistemas del organismo