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This seems paradoxical given that the supplement contains fiber and butyrate-producing bacteria, but it can happen when the gut microbiome shifts create temporary motility changes

Joint Pain and Connective Tissue Weakness: As an essential cofactor for the enzymes that synthesize collagen, vitamin C promotes the structural integrity and repair of blood vessels, ligaments, and joints, helping to alleviate the deep connective tissue pain often experienced by patients with systemic inflammation

However, younger adults are not safe, and B12 deficiency can result from stress, poor nutrition and certain medications like antacids or diabetes drugs

J., Li, H., Kim, M., DAgati, V