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The patient was given a final diagnosis of MMNST

Serum limitation-induced senescent fibroblasts model and effect of FOXO4-DRI Passage 3 fibroblasts derived from keloids and normal skins were cultured in a Dulbeccos Modified Eagles medium (DMEM, Hyclone, Logan, Utah, USA) containing 10% fetal bovine serum (FBS, Gibco, Grand Island, NY, USA) to 90% confluence, and then cultured in a DMEM containing 2% FBS for 3 days to construct a serum limitation-induced senescent fibroblast model

Afamelanotide Afamelanotide , sold under the brand name Scenesse , is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria, [1] [2] [4] a rare form of genetic sun sensitivity