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10.3390/metabo1412067939728460 80 Cutler RG, Camandola S, Feldman NH, et al

a , GO categories that are significantly enriched among genes up- or down-regulated in liver of KO compared to Het mice on No Cys diet

Both types of PE-AA oxidation, enzymatic (by lipoxygenase) and non-enzymatic (by autooxidation to PE-AA-OOH), eventually result in cell death [18, 30,31,32]

In contrast, ZIP1 is downregulated in malignant cells, resulting in the inability to accumulate zinc