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It also improved the proliferative and secretory functions of fibroblasts and reversed morphological abnormalities of senescent cells (such as flattened cell shape, enlarged volume, and nuclear pyknosis)

10.1074/mcp.m500279-mcp200 622 UverskyV

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Colitis-associated cancer research: A 2016 study found that KPV reduced tumor development in a murine model of colitis-associated colon cancer, suggesting that its ability to dampen chronic gut inflammation may interrupt the inflammation-to-cancer progression that drives some colorectal cancers