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Production, scavenging, and role in cell signaling

Synthesis of D-P H-His(Trt)-OMeHCl (5.0 g, 11.15 mmol), Boc-Gly-OH (2.15 g, 12.25 mmol), HATU (8.5 g, 22.35 mmol) and HOAT (3.0 g, 22.35 mmol) were dissolved in DMF (80 mL) under nitrogen atmosphere and ice bath conditions

The homoserine hydroxyl group is then activated by phosphate, succinyl, or acetyl groups, and the hydroxyl group is then replaced by cysteine, methyl thiol, or hydrogen sulfide by displacement reactions

This gentle nature is why its often called the Glow Peptide. It helps improve skin texture and firmness without stripping its protective barrier