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THSG increased tyrosinase activity in a dose-dependent manner at concentrations ranging from 1 to 10 g/ml (Jiang et al., 2009)

As a fat soluble vitamin, Vit A readily penetrates the cell membrane and scavenges lipid peroxidation derived free radicals and other reactive species by regulating the activation of stimulated by retinoic acid 6 (STRA6), thereby alleviating oxidative stress [30]

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