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Because GSH may oxidize after collection and GSSG is typically much less abundant, sample handling can substantially alter the apparent balance

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Genetically, ferroptosis is associated with altered expression of key genes, such as glutathione peroxidase 4 (GPX4), acyl-CoA synthetase long-chain family member 4 (ACSL4), and prostaglandin-endoperoxide synthase 2 (PTGS2)

Dar found that when PA infected epithelial cells, M1-activated macrophages expressed iNOS/NO in the host immune cells, which could make the cells resistant to ferroptosis [47]