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Gallbladder-related adverse events, including cholelithiasis and cholecystitis, are uncommon with tirzepatide therapy

The tumor microenvironment (TME), comprising immune cells (e.g., myeloid-derived suppressor cells, tumor-associated macrophages), stromal fibroblasts, and vascular endothelial cells, exploits this inflammatory circuitry by repurposing cytokines like IL-1 and IFN- to activate invasion-associated MMPs and immune-evasion pathways (Figure 4) (Wang et al., 2024)

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PRP treatment holds promise in promoting tissue healing and repair