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The pathophysiology of HS is complex but involves follicular hyperkeratosis/occlusion, sweat gland dysfunction, immune dysregulation, bacterial infections, and chronic local and systemic inflammation
If a lesion visualised after tape stripping is much lighter (with regular structures), this is likely to be reassuring As discussed in the chapter Melanoma - an overview the dermoscopic examination of melanocytic lesions requires considerable experience In terms of benign and malignant lesions on the palms and soles refer to the chapter Melanoma: acral lentiginous melanoma
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