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A limited number of preclinical studies suggest that berberine may modestly increase endogenous GLP-1 secretion from intestinal L-cells, potentially through effects on gut microbiota or direct stimulation of enteroendocrine cells

If any of the following apply to you, you should avoid taking Ozempic for weight loss: If youre interested in taking Ozempic to help lose weight and any of the above symptoms or conditions apply to you, talk to your healthcare provider about alternatives that may be appropriate

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One of the most extensive studies to date, performed by the Diabetes Prevention Program (DPP) and published in 2012, tested metformin in people with prediabetes